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Impurities are chemical substances inside a confined amount of a sample which differ from the chemical composition of the compound of interest. In pharmaceutical world, an impurity is generally considered as an other organic material beside the other drug substances that is arises out of the synthesis most of the time, inorganic contaminants are not considered as an impurity unless they are toxic, such as heavy metal or arsenic.
Natural products are any organic compounds that are synthesized by a living organism, including those small molecules produced by organisms as primary and secondary metabolites. There are also other organic compounds produced naturally, some of extraordinary complexity, which are not primary metabolites. Natural products have high structural diversity and unique pharmacological or biological activities due to the natural selection and evolutionary processes that have shaped their utility over hundreds of thousands of years.
Isotopically labeled compounds are non-radioactive chemical substances where one or more element within a compound has been substituted for its stable isotope. These compounds have been synthesized and utilized by scientists from various areas of biomedical research during the last several decades. Compounds labeled with stable isotopes, have been used effectively by drug metabolism scientists and toxicologists to gain better understanding of drugs’ disposition and their potential role in target organ toxicities.
Peptides play a crucial role in fundamental physiological and biochemical processes and are essential to many aspects of biomedical research especially as the pharmaceutical industry continues to shift more towards biologicals for new drug candidates. When compared to traditional small molecule drugs, pharmaceutical peptides are considered to be safer for application in vivo as a result of their natural origin and their non-toxic metabolites (amino acids).
(Active Pharmaceutical Ingredient) means the active ingredient which is contained in medicine. For example, an active ingredient to relieve pain is included in a painkiller. This is called API. A small amount of the active ingredient has an effect, so only a tiny part of the active ingredient is contained in medicine. You will find the name and amount of the active ingredient contained in the medicine on the package of drugs.